Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.

doi:10.1038/npp.2009.81

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Article

Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2009

Perroud Nader, Aitchison Katherine J, Uher Rudolf, Smith Rebecca, Huezo-Diaz Patricia, Marusic Andrej, Maier Wolfgang, Mors Ole, Placentino Anna, Henigsberg Neven, Rietschel Marcella, Hauser Joanna, Souery Daniel, Kapelski Pawel, Bonvicini Cristian, Zobel Astrid, Jorgensen Lisbeth, Petrovic Ana, Kalember Petra, Schulze Thomas G, Gupta Bhanu, Gray Joanna, Lewis Cathryn M, Farmer Anne E, McGuffin Peter, Craig Ian

Abstract excerpt

The aim of this study was to investigate genetic predictors of an increase in suicidal ideation during treatment with a selective serotonin reuptake inhibitor or a tricyclic antidepressant. A total of 796 adult patients with major depressive disorder who were treated with a flexible dosage of escitalopram or nortriptyline in Genome-based Therapeutic Drugs for Depression (GENDEP) were included in the sample and...

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Identifiers

PMID: 19641488
DOI: 10.1038/npp.2009.81

Genes

BDNF
NTRK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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