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Article

Suicide behavior as a quantitative trait and its genetic background.

Journal of affective disorders - 1 Dec 2016

Pawlak Joanna, Dmitrzak-Weglarz Monika, Wilkosc Monika, Szczepankiewicz Aleksandra, Leszczynska-Rodziewicz Anna, Zaremba Dorota, Kapelski Pawel, Rajewska-Rager Aleksandra, Hauser Joanna

Abstract excerpt

INTRODUCTION: Studies have not given yet a clear answer what is the genetic background of suicidal predisposition. The associations between polymorphisms of the TPH1 and 5-HTTLPR genes and violent suicidal behavior was revealed with the least inconsistencies. METHOD: We selected 10 "strong candidate genes" and 35 SNPs, SLC6A4 and ACP1 for replication study. We searched associations between precisely described...

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Topics

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Share to CRF Receptor, Type 1
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor, Serotonin, 5-HT2A

Share to Receptors, Corticotropin-Releasing Hormone

Share to Suicidal Ideation

Share to Suicide

Share to Suicide, Attempted

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 27479537
DOI: 10.1016/j.jad.2016.07.029

Genes

ACP1
TPH1
CRHR1
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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