Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative expression of the mutated lamin A/C gene in patients with cardiolaminopathy.

Journal of the American College of Cardiology - 6 Nov 2012

Narula Nupoor, Favalli Valentina, Tarantino Paolo, Grasso Maurizia, Pilotto Andrea, Bellazzi Riccardo, Serio Alessandra, Gambarin Fabiana I, Charron Philippe, Meder Benjamin, Pinto Yigal, Elliott Perry M, Mogensen Jens, Bolognesi Martino, Bollati Michela, Arbustini Eloisa

Abstract excerpt

OBJECTIVES: The authors sought to investigate the gene and protein expression in Lamin A/C (LMNA)-mutated dilated cardiolaminopathy (DCM) patients (DCM(LMNAMut)) versus LMNA-wild-type DCM (DCM(LMNAWT)), and normal controls (CTRL(LMNAWT)). BACKGROUND: Dilated cardiolaminopathies are clinically characterized by high arrhythmogenic risk and caused by LMNA mutations. Little is known regarding quantitative gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to LMNA gene

Share to Haplotypes

Share to Lamin Type A

Share to Mutation

Share to RNA, Messenger

Source

Identifiers

PMID: 23062543
DOI: 10.1016/j.jacc.2012.05.059

Genes

LMNA
CTRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative expression of the mutated lamin A/C gene in patients with cardiolaminopathy.PMID 23062543Read ↗

Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy.Semantic proximity Read ↗

Natural history of dilated cardiomyopathy due to lamin A/C gene mutations.Semantic proximity Read ↗

Can Circulating Cardiac Biomarkers Be Helpful in the Assessment of LMNA Mutation Carriers?Semantic proximity Read ↗

Autosomal dominant dilated cardiomyopathy with atrioventricular block: a lamin A/C defect-related disease.Semantic proximity Read ↗

Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers.Semantic proximity Read ↗

An LMNA synonymous variant associated with severe dilated cardiomyopathy: Case report.Semantic proximity Read ↗

High yield of LMNA mutations in patients with dilated cardiomyopathy and/or conduction disease referred to cardiogenetics outpatient clinics.Semantic proximity Read ↗

Long-term outcome and risk stratification in dilated cardiolaminopathies.Semantic proximity Read ↗

Genetic and ultrastructural studies in dilated cardiomyopathy patients: a large deletion in the lamin A/C gene is associated with cardiomyocyte nuclear envelope disruption.Semantic proximity Read ↗

Severe myocardial fibrosis caused by a deletion of the 5' end of the lamin A/C gene.Semantic proximity Read ↗

Pro‐inflammatory cytokines as emerging molecular determinants in cardiolaminopathiesSemantic proximity Read ↗

Lamin A/C mutation analysis in a cohort of 324 unrelated patients with idiopathic or familial dilated cardiomyopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.