Article
Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) - 1 Aug 2018
Toro Rocío, Blasco-Turrión Sara, Morales-Ponce Francisco José, Gonzalez Pablo, Martínez-Camblor Pablo, López-Granados Amador, Brugada Ramon, Campuzano Oscar, Pérez-Serra Alexandra, Rosa Longobardo Felix, Mangas Alipio, Llorente-Cortes Vicenta, de Gonzalo-Calvo David
Abstract excerpt
Lamin A/C gene (LMNA)-related familial dilated cardiomyopathy (fDCM) is an aggressive heart disease that often leads to transplantation and sudden death. The aim of our study was to evaluate the circulating microRNA (miRNA) profiles of patients with LMNA pathogenic mutations. The study population (N = 75) included (i) patients with pathogenic LMNA mutations responsible for fDCM (LMNAMUT), (ii) age- and...
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