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Article

Severe myocardial fibrosis caused by a deletion of the 5' end of the lamin A/C gene.

Journal of the American College of Cardiology - 26 Jun 2007

van Tintelen J Peter, Tio Rene A, Kerstjens-Frederikse Wilhelmina S, van Berlo Jop H, Boven Ludolf G, Suurmeijer Albert J H, White Stefan J, den Dunnen Johan T, te Meerman Gerard J, Vos Yvonne J, van der Hout Annemarie H, Osinga Jan, van den Berg Maarten P, van Veldhuisen Dirk J, Buys Charles H C M, Hofstra Robert M W, Pinto Yigal M

Abstract excerpt

OBJECTIVES: The goal of this study was to identify the underlying gene defect in a family with inherited myocardial fibrosis. BACKGROUND: A large family with an autosomal dominantly inherited form of myocardial fibrosis with a highly malignant clinical outcome has been investigated. Because myoca...

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Source

Identifiers

PMID: 17599607
DOI: 10.1016/j.jacc.2007.02.063

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17599607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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