Associations between inflammasome-related gene NLRP3 Polymorphisms (rs10754558 and rs35829419) and risk of bladder cancer in a Chinese population.

doi:10.1002/jcla.23973

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Associations between inflammasome-related gene NLRP3 Polymorphisms (rs10754558 and rs35829419) and risk of bladder cancer in a Chinese population.

Journal of clinical laboratory analysis - 1 Nov 2021

Xu Gang, Huang Ruohui, Xia Wei, Jiang Bo, Xiao Guancheng, Li Yanmin

Abstract excerpt

BACKGROUND: NLRP3 inflammasome as a component of immune system has been found related to several cancers, but no study has assessed NLRP3 polymorphisms on risk of bladder cancer (BC). We aim to investigate whether NLRP3 polymorphisms are associated with the risk and clinical features of bladder cancer (BC) in a Chinese population. METHODS: Genotype frequency of two commonly studied NLRP3 SNPs (rs10754558 and...

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PMID: 34636069
DOI: 10.1002/jcla.23973
PMCID: PMC8605168

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