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Article

Role of the NC-loop in catalytic activity and stability in lipase from Fervidobacterium changbaicum.

PloS one - 1 Jan 2012

Li Binchun, Yang Guangyu, Wu Lie, Feng Yan

Abstract excerpt

Flexible NC-loops between the catalytic domain and the cap domain of the α/β hydrolase fold enzymes show remarkable diversity in length, sequence, and configuration. Recent investigations have suggested that the NC-loop might be involved in catalysis and substrate recognition in many enzymes from the α/β hydrolase fold superfamily. To foster a deep understanding of its role in catalysis, stability, and divergent...

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Identifiers

PMID: 23056508
DOI: 10.1371/journal.pone.0046881
PMCID: PMC3466181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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