Article
Neurofibromin 1 is a miRNA target in neurons.
PloS one - 1 Jan 2012
Paschou Maria, Doxakis Epaminondas
Abstract excerpt
Mutations of the neurofibromin 1 gene cause neurofibromatosis type 1, a disease in which learning and behavioral abnormalities are common. The disease is completely penetrant but shows variable phenotypic expression in patients. The repertoire of regulatory interactions utilized by neurons to control neurofibromin 1 expression is poorly understood. Here, we examined the contribution of microRNAs into this...
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