Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA‐10b regulates tumorigenesis in neurofibromatosis type 1

12 May 2010

Abstract excerpt

MicroRNAs (miRNAs) are frequently deregulated in human tumors, and play important roles in tumor development and progression. The pathological roles of miRNAs in neurofibromatosis type 1 (NF1) tumorigenesis are largely unknown. We demonstrated that miR-10b was up-regulated in primary Schwann cells isolated from NF1 neurofibromas and in cell lines and tumor tissues from malignant peripheral nerve sheath tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tumor Diagnosis and Treatments
Share to Neurofibromatosis and Schwannoma Cases
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20550523
DOI: 10.1111/j.1349-7006.2010.01616.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA‐10b regulates tumorigenesis in neurofibromatosis type 1PMID 20550523Read ↗

MicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesisSemantic proximity Read ↗

An emerging role for microRNAs in NF1 tumorigenesis.Semantic proximity Read ↗

The Activation of the WNT Signaling Pathway Is a Hallmark in Neurofibromatosis Type 1 TumorigenesisSemantic proximity Read ↗

Global microRNA profiling identified miR‐10b‐5p as a regulator of neurofibromatosis 1 (NF1)‐glioma migrationSemantic proximity Read ↗

MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progressionSemantic proximity Read ↗

Past, Present, and Future Therapeutic Strategies for NF-1-Associated Tumors.Semantic proximity Read ↗

Tumor Suppressor Mutations and Growth Factor Signaling in the Pathogenesis of NF1-Associated Peripheral Nerve Sheath TumorsSemantic proximity Read ↗

MicroRNA-193b Enhances Tumor Progression via Down Regulation of Neurofibromin 1Semantic proximity Read ↗

Decreased expression of neurofibromin contributes to epithelial–mesenchymal transition in neurofibromatosis type 1Semantic proximity Read ↗

Neurofibromatosis 1.Semantic proximity Read ↗

Genome‐wide transcriptome analyses reveal p53 inactivation mediated loss of miR‐34a expression in malignant peripheral nerve sheath tumoursSemantic proximity Read ↗

RAS/MEK-independent gene expression reveals BMP2-related malignant phenotypes in the Nf1-deficient MPNST.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.