Article
An emerging role for microRNAs in NF1 tumorigenesis.
Human genomics - 17 Nov 2012
Sedani Ashni, Cooper David N, Upadhyaya Meena
Abstract excerpt
MicroRNAs (miRNAs) are a class of non-coding RNA, which have recently been shown to have a wide variety of regulatory functions in relation to gene expression. Since their identification nearly 20 years ago, miRNAs have been found to play an important role in cancer, including in neurofibromatosis type 1 (NF1)-associated tumours. NF1 is the most commonly inherited tumour predisposition syndrome and can lead to...
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