Mechanistic insights from animal models of neurofibromatosis type 1 cognitive impairment

Abstract excerpt

Neurofibromatosis type 1 (NF1) is an autosomal-dominant neurogenetic disorder caused by mutations in the gene neurofibromin 1 (NF1). NF1 predisposes individuals to a variety of symptoms, including peripheral nerve tumors, brain tumors and cognitive dysfunction. Cognitive deficits can negatively impact patient quality of life, especially the social and academic development of children. The neurofibromin protein...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Meningioma and schwannoma management
• Share to Neurofibromatosis and Schwannoma Cases
• Share to Vascular Malformations Diagnosis and Treatment