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Article

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

2 Oct 2012

Abstract excerpt

RATIONALE: Globally there are approximately 9 million new active tuberculosis cases and 1.4 million deaths annually. Effective antituberculosis treatment monitoring is difficult as there are no existing biomarkers of poor adherence or inadequate treatment earlier than 2 months after treatment initiation. Inadequate treatment leads to worsening disease, disease transmission and drug resistance. OBJECTIVES: To...

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PMID: 23056259
DOI: 10.1371/journal.pone.0046191

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