Article

Blood transcriptomic signatures predict poor treatment outcomes in drug-susceptible pulmonary TB in Brazil

2025-10-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Non-sputum biomarkers to monitor tuberculosis (TB) treatment and predict poor outcomes are lacking. We evaluated host-blood transcriptomic signatures for treatment monitoring and prognosis (death, treatment failure, recurrence) in adults with pulmonary TB. <h4>Methods</h4> Adults with culture-confirmed, drug-susceptible pulmonary TB were enrolled at five Brazilian sites. Wh...

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Literature Corpus work: 8695da5f-f794-5eaf-8a19-8d6448327d58
DOI: 10.1101/2025.10.07.25337480

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