Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Signature required: The transcriptional response to tuberculosis.

The Journal of experimental medicine - 6 Dec 2021

Barry Clifton E, Mayer-Barber Katrin D

Abstract excerpt

The majority of humans infected with Mycobacterium tuberculosis never experience clinical symptoms or signs, but predicting those who will remains out of reach. Here, we discuss recent studies that reveal patterns and pathways that determine who is at highest risk for progression.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression
Share to Genetic Predisposition to Disease
Share to Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Latent Tuberculosis

Share to Mycobacterium tuberculosis

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 34779817
DOI: 10.1084/jem.20211665
PMCID: PMC8598054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Signature required: The transcriptional response to tuberculosis.PMID 34779817Read ↗

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection.Semantic proximity Read ↗

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infectionSemantic proximity Read ↗

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis TherapySemantic proximity Read ↗

Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Identifies Diagnostic Biomarkers That Distinguish Active and Latent TuberculosisSemantic proximity Read ↗

A 380-gene meta-signature of active tuberculosis compared with healthy controlsSemantic proximity Read ↗

Host- and pathogen-related determinants of pulmonary versus extrapulmonary tuberculosis.Semantic proximity Read ↗

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary TuberculosisSemantic proximity Read ↗

Concise whole blood transcriptional signatures for incipient tuberculosis: A systematic review and patient-level pooled meta-analysisSemantic proximity Read ↗

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosisSemantic proximity Read ↗

Identification of host gene expression biomarkers for tuberculosisSemantic proximity Read ↗

RISK6 as a Translational Host Transcriptomic Signature for Tuberculosis Diagnosis, Treatment Monitoring, and Risk StratificationSemantic proximity Read ↗

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.