Article
Toll-like receptor 4 (TLR4) polymorphisms in Iranian patients with visceral leishmaniasis.
Molecular biology reports - 1 Dec 2012
Rasouli Manoochehr, Keshavarz Maryam, Kalani Mehdi, Moravej Ali, Kiany Simin, Badiee Parisa
Abstract excerpt
The role of Toll-like receptor (TLR) 4 in visceral leishmaniasis (VL), a disease caused by an obligate intracellular protozoan parasites belonging to the genus Leishmania, has been shown in the recent leishmaniasis experimental studies. As genetic host factors play an important role in the susceptibility and/or resistance to VL, the association between TLR4 gene mutations [A896G and C1196T single nucleotide...
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