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Article

Specific acquisition of functional CD59 but not CD46 or CD55 by hepatitis C virus.

PloS one - 1 Jan 2012

Ejaz Asim, Steinmann Eike, Bánki Zoltán, Anggakusuma, Khalid Sana, Lengauer Susanne, Wilhelm Corinne, Zoller Heinz, Schloegl Anna, Steinmann Joerg, Grabski Elena, Kleines Michael, Pietschmann Thomas, Stoiber Heribert

Abstract excerpt

Viruses of different families encode for regulators of the complement system (RCAs) or acquire such RCAs from the host to get protection against complement-mediated lysis (CML). As hepatitis C virus (HCV) shares no genetic similarity to any known RCA and is detectable at high titers in sera of infected individuals, we investigated whether HCV has adapted host-derived RCAs to resist CML. Here we report that HCV...

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Share to CD55 Antigens
Share to CD59 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Complement System Proteins

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Share to Immunoglobulin G

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Source

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Identifiers

PMID: 23049856
DOI: 10.1371/journal.pone.0045770
PMCID: PMC3458075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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