Article
HIV-1 and HIV-2 isolates differ in their ability to activate the complement system on the surface of infected cells.
AIDS (London, England) - 1 Jul 1993
Marschang P, Gürtler L, Tötsch M, Thielens N M, Arlaud G J, Hittmair A, Katinger H, Dierich M P
Abstract excerpt
OBJECTIVE: To analyse the ability of different HIV-1 and HIV-2 isolates to activate the complement system. DESIGN: H9 cells chronically infected with various HIV isolates and the corresponding purified viruses were tested for complement activation. To identify the molecules responsible for comple...
Topics
- Antigens, CD
- CD55 Antigens
- CD59 Antigens
- Cell Membrane
- Cells, Cultured
- Complement Activation
- Complement C3
- Complement Inactivator Proteins
- Enzyme-Linked Immunosorbent Assay
- Fluorescent Antibody Technique
- Genetic Variation
- HIV Envelope Protein gp41
- HIV-1
- HIV-2