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Article

A genetic locus in 7p12.2 associated with treatment resistant schizophrenia.

Schizophrenia research - 1 Nov 2014

Li Jiang, Meltzer Herbert Y

Abstract excerpt

Approximately 30% of patients with schizophrenia are treatment resistant (TRS), i.e. have persistent psychotic symptoms despite adequate trials of at least two antipsychotic drugs (APDs). Most TRS patients are candidates for clozapine treatment which is underutilized because of its side effects and difficulty in identifying TRS. We conducted a genome-wide association study (GWAS) of 79 TRS and 95 non-treatment...

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Source

Identifiers

PMID: 25223841
DOI: 10.1016/j.schres.2014.08.018

Genes

DDC
GRB10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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