Article
[Effect of AKR7A1 overexpression on crotonaldehyde-induced mutagenicity in V79-4 cells].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 Oct 2012
Li Dan, Zhang Qi-shan, Chu Yang
Abstract excerpt
AIM: To investigate the effect of overexpressing rat aldo-keto reductases (AKR7A1) in V79-4 cells on crotonaldehyde-induced mutagenicity. METHODS: The expression level and enzyme activity of AKR7A1 protein expressed in V79-4 cells were measured by Western blotting and AKR enzyme assay, respectively. HGPRT assay was applied to evaluate the effect of AKR7A1 overexpression on crotonaldehyde-induced mutagenicity in...
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