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Article

Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.

BMC genomics - 10 Oct 2012

Monestier Olivier, Brun Caroline, Heu Katy, Passet Bruno, Malhouroux Mélanie, Magnol Laetitia, Vilotte Jean-Luc, Blanquet Véronique

Abstract excerpt

BACKGROUND: Myostatin, a member of the TGFβ superfamily, is well known as a potent and specific negative regulator of muscle growth. Targeting the myostatin signalling pathway may offer promising therapeutic strategies for the treatment of muscle-wasting disorders. In the last decade, various myostatin-binding proteins have been identified to be able to inhibit myostatin activity. One of these is GASP1 (Growth...

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Identifiers

PMID: 23046573
DOI: 10.1186/1471-2164-13-541
PMCID: PMC3575399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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