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Article

Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin.

Mutation research - 1 Feb 1990

Imanishi H, Sasaki Y F, Matsumoto K, Watanabe M, Ohta T, Shirasu Y, Tutikawa K

Abstract excerpt

The antimutagenic effects of vanillin, anisaldehyde, cinnamaldehyde and coumarin were investigated in cultured Chinese hamster V79 cells in vitro. The frequencies of 6-TG-resistant mutations induced by UV or X-rays were decreased by treatment with each compound during the expression time. These decreases were not due to cytotoxic effects on cellular growth or killing effects on damaged cells. The antimutagenic...

Topics

Acrolein
Animals
Benzaldehydes
Cells, Cultured
Coumarins
Drug Resistance
Ethylnitrosourea
Female
Male
Mice
Mice, Inbred C57BL
Mutagenicity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Pregnancy

Thioguanine

Ultraviolet Rays

X-Rays

Source

Identifiers

PMID: 2304483
DOI: 10.1016/0165-7992(90)90038-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2304483-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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