Suppression of in vitro chemical transformation by the carcinogenesis-promoting, viable yellow gene Avy.

doi:10.1093/carcin/12.7.1157

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Article

Suppression of in vitro chemical transformation by the carcinogenesis-promoting, viable yellow gene Avy.

Carcinogenesis - 1 Jul 1991

Furst A S, Becker F F

Abstract excerpt

The presence of the viable yellow Avy and lethal yellow Ay genes has been demonstrated to accelerate the process of tumorigenesis in mice bearing genetically, chemically or virally initiated cells. This promoting effect has been reported in the liver, lung, breast, bladder and skin. Although it h...

Topics

Animals
Cell Division
Cell Transformation, Neoplastic
Cells, Cultured
Genes
Genetic Predisposition to Disease
Methylnitronitrosoguanidine
Mice
Mice, Inbred C57BL
Mutation
Neoplasms, Experimental

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