Article
Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair.
Mutation research - 1 Mar 2007
King Audrey A, Shaughnessy Daniel T, Mure Kanae, Leszczynska Joanna, Ward William O, Umbach David M, Xu Zongli, Ducharme Danica, Taylor Jack A, Demarini David M, Klein Catherine B
Abstract excerpt
Vanillin (VAN) and cinnamaldehyde (CIN) are dietary flavorings that exhibit antimutagenic activity against mutagen-induced and spontaneous mutations in bacteria. Although these compounds were antimutagenic against chromosomal mutations in mammalian cells, they have not been studied for antimutagenesis against spontaneous gene mutations in mammalian cells. Thus, we initiated studies with VAN and CIN in human...
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