A sensitive assay for detecting mutations resulting from unequal homologous recombination without phenotypic selection.

doi:10.1016/0165-7992(90)90035-i

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Article

A sensitive assay for detecting mutations resulting from unequal homologous recombination without phenotypic selection.

Mutation research - 1 Feb 1990

Kominami R

Abstract excerpt

Naturally occurring mutations are composed of a large number of mutations of many types that include mutations resulting from unequal homologus recombination between repetitive elements. The present paper describes a sensitive method for detecting such mutations without phenotypic selection. This...

Topics

Animals
Blotting, Southern
DNA, Ribosomal
Drug Resistance
Methylnitronitrosoguanidine
Mice
Mice, Inbred BALB C
Mitosis
Mutagenicity Tests
Phenotype
Recombination, Genetic
Repetitive Sequences, Nucleic Acid
Selection, Genetic
Tetradecanoylphorbol Acetate

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