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Article

Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 2000

Yoon J, Ben-Ami H C, Hong Y S, Park S, Strong L L, Bowman J, Geng C, Baek K, Minke B, Pak W L

Abstract excerpt

The Drosophila trp gene encodes a light-activated Ca(2+) channel subunit, which is a prototypical member of a novel class of channel proteins. Previously identified trp mutants are all recessive, loss-of-function mutants characterized by a transient receptor potential and the total or near-total loss of functional TRP protein. Although retinal degeneration does occur in these mutants, it is relatively mild and...

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PMID: 10632594
PMCID: PMC6772429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.PMID 10632594Read ↗

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