Article
Embryonic stem cell therapy of heart failure in genetic cardiomyopathy.
Stem cells (Dayton, Ohio) - 1 Oct 2008
Yamada Satsuki, Nelson Timothy J, Crespo-Diaz Ruben J, Perez-Terzic Carmen, Liu Xiao-Ke, Miki Takashi, Seino Susumu, Behfar Atta, Terzic Andre
Abstract excerpt
Pathogenic causes underlying nonischemic cardiomyopathies are increasingly being resolved, yet repair therapies for these commonly heritable forms of heart failure are lacking. A case in point is human dilated cardiomyopathy 10 (CMD10; Online Mendelian Inheritance in Man #608569), a progressive organ dysfunction syndrome refractory to conventional therapies and linked to mutations in cardiac ATP-sensitive K(+)...
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