Article
Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease.
Clinical and experimental immunology - 1 Nov 2012
Arakawa Y, Watanabe M, Inoue N, Sarumaru M, Hidaka Y, Iwatani Y
Abstract excerpt
To clarify the association between factors regulating DNA methylation and the prognosis of autoimmune thyroid diseases (AITDs), we genotyped single nucleotide polymorphisms in genes encoding DNA methyltransferase 1 (DNMT1), DNMT3A, DNMT3B, methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR), which are enzymes essential for DNA methylation. Subjects for this study included 125...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
