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Article

Methylation levels of the TNFA gene are different between Graves' and Hashimoto's diseases and influenced by the TNFA polymorphism.

Autoimmunity - 1 May 2018

Morita Emi, Watanabe Mikio, Inoue Naoya, Hashimoto Hidemi, Haga Emi, Hidaka Yoh, Iwatani Yoshinori

Abstract excerpt

Graves' disease (GD) and Hashimoto's disease (HD) are different pathological types of autoimmune thyroid diseases (AITDs). However, the epigenetic differences between these diseases have not been elucidated. DNA methylation is one of the primary epigenetic modifications that reflect environmental influences on gene expression. In this study, we evaluated the methylation status of six CpG sites in the TNFA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29526119
DOI: 10.1080/08916934.2018.1448078

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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