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Article

A novel method for genotyping the Helicobacter pylori vacA intermediate region directly in gastric biopsy specimens.

Journal of clinical microbiology - 1 Dec 2012

Ferreira Rui M, Machado Jose C, Letley Darren, Atherton John C, Pardo Maria L, Gonzalez Carlos A, Carneiro Fatima, Figueiredo Ceu

Abstract excerpt

The present report describes a novel method for genotyping the virulence-associated vacA intermediate (i) region of Helicobacter pylori in archive material. vacA i-region genotypes as determined by the novel method were completely concordant with those of sequence analysis and with those of functional vacuolation activity. The method was further validated directly in gastric biopsy specimens of 386 H....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23035185
DOI: 10.1128/JCM.02087-12
PMCID: PMC3502994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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