Article
One-step polymerase chain reaction-based typing of Helicobacter pylori vacA gene: association with gastric histopathology.
Medical microbiology and immunology - 1 Dec 1999
Han S R, Schneider T, Loos M, Bhakdi S, Maeurer M J
Abstract excerpt
Heterogeneity of the Helicobacter pylori vacA gene may be associated with bacterial virulence and presentation. In this study, the possible correlation between vacA genotypes and gastric histopathology was investigated. Using a modified one-step polymerase chain reaction (PCR)-based method, 122 of 131 H. pylori isolates obtained from 63 of 67 patients from Germany were classified into distinct vacA genotypes...
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