Article
Relevance of Helicobacter pylori vacA 3'-end Region Polymorphism to Gastric Cancer.
Helicobacter - 1 Aug 2016
Bakhti Seyedeh Zahra, Latifi-Navid Saeid, Mohammadi Shiva, Zahri Saber, Bakhti Fatemeh Sadat, Feizi Farideh, Yazdanbod Abbas, Siavoshi Farideh
Abstract excerpt
BACKGROUND: Helicobacter pylori vacA genotypes play an important role in the pathogenesis of severe gastrointestinal disease. MATERIALS AND METHODS: We identified a novel polymorphic site in the 3'-end region of H. pylori vacA gene, denoted by c1/-c2 (c1: with deletion of 15 bp), and examined associations of this and the previous four sites as well as cagA status with gastroduodenal diseases, in a total of 217...
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