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Article

Approaching Shared Pathophysiology in Immune-Mediated Diseases through Functional Genomics.

Genes - 9 Dec 2020

González-Serna David, Villanueva-Martin Gonzalo, Acosta-Herrera Marialbert, Márquez Ana, Martín Javier

Abstract excerpt

Immune-mediated diseases (IMDs) are complex pathologies that are strongly influenced by environmental and genetic factors. Associations between genetic loci and susceptibility to these diseases have been widely studied, and hundreds of risk variants have emerged during the last two decades, with researchers observing a shared genetic pattern among them. Nevertheless, the pathological mechanism behind these...

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Epigenomics
Gene Expression Profiling
Genetic Loci
Genome-Wide Association Study
Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immune System Diseases

Regulatory Sequences, Nucleic Acid

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PMID: 33317201
DOI: 10.3390/genes11121482
PMCID: PMC7762979

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