Article
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2012
Surakka Ida, Whitfield John B, Perola Markus, Visscher Peter M, Montgomery Grant W, Falchi Mario, Willemsen Gonneke, de Geus Eco J C, Magnusson Patrik K E, Christensen Kaare, Sørensen Thorkild I A, Pietiläinen Kirsi H, Rantanen Taina, Silander Kaisa, Widén Elisabeth, Muilu Juha, Rahman Iffat, Liljedahl Ulrika, Syvänen Ann-Christine, Palotie Aarno, Kaprio Jaakko, Kyvik Kirsten O, Pedersen Nancy L, Boomsma Dorret I, Spector Tim, Martin Nicholas G, Ripatti Samuli, Peltonen Leena
Abstract excerpt
Genome-wide association analysis on monozygotic twin-pairs offers a route to discovery of gene environment interactions through testing for variability loci associated with sensitivity to individual environment/lifestyle. We present a genome-wide scan of loci associated with intra-pair differences in serum lipid and apolipoprotein levels. We report data for 1,720 monozygotic female twin-pairs from GenomEUtwin...
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