Article
Twin studies in metabolic diseases.
Annals of medicine - 1 Oct 1992
Koskenvuo M, Kaprio J, Romanov K
Abstract excerpt
The traditional role of twin studies has been to assess the relative role of genetic factors as a first step in defining the genetic architecture of complex traits. This has been based on the realization that monozygotic pairs (MZ) share all their genes, while dizygotic pairs (DZ) share 50% of their genes on average. Thus, greater similarity of MZ pairs compared to DZ pairs has been taken as prima facie evidence...
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