Article
Effect of genome and environment on metabolic and inflammatory profiles.
PloS one - 1 Jan 2015
Sirota Marina, Willemsen Gonneke, Sundar Purnima, Pitts Steven J, Potluri Shobha, Prifti Edi, Kennedy Sean, Ehrlich S Dusko, Neuteboom Jacoline, Kluft Cornelis, Malone Karen E, Cox David R, de Geus Eco J C, Boomsma Dorret I
Abstract excerpt
Twin and family studies have established the contribution of genetic factors to variation in metabolic, hematologic and immunological parameters. The majority of these studies analyzed single or combined traits into pre-defined syndromes. In the present study, we explore an alternative multivariate approach in which a broad range of metabolic, hematologic, and immunological traits are analyzed simultaneously to...
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