Article
A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins.
Human reproduction (Oxford, England) - 1 Jun 2010
Painter Jodie N, Willemsen Gonneke, Nyholt Dale, Hoekstra Chantal, Duffy David L, Henders Anjali K, Wallace Leanne, Healey Sue, Cannon-Albright Lisa A, Skolnick Mark, Martin Nicholas G, Boomsma Dorret I, Montgomery Grant W
Abstract excerpt
BACKGROUND: The tendency to conceive dizygotic (DZ) twins is a complex trait influenced by genetic and environmental factors. To search for new candidate loci for twinning, we conducted a genome-wide linkage scan in 525 families using microsatellite and single nucleotide polymorphism marker panels. METHODS AND RESULTS: Non-parametric linkage analyses, including 523 families containing a total of 1115 mothers of...
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