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Article

Infections associated with chronic granulomatous disease: linking genetics to phenotypic expression.

Expert review of anti-infective therapy - 1 Aug 2012

Ben-Ari Josef, Wolach Ofir, Gavrieli Ronit, Wolach Baruch

Abstract excerpt

Chronic granulomatous disease (CGD) is an inherited primary immunodeficiency characterized by the absence or malfunction of the NADPH oxidase in phagocytic cells. As a result, there is an impaired ability to generate superoxide anions and the subsequent reactive oxygen intermediates. Consequently, CGD patients suffer from two clinical manifestations: recurrent, life-threatening bacterial and fungal infections and...

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Identifiers

PMID: 23030328
DOI: 10.1586/eri.12.77

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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