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Article

The genetic basis of chronic granulomatous disease.

Immunological reviews - 1 Apr 1994

Roos D

Abstract excerpt

Chronic granulomatous disease is a serious clinical entity. The disease is caused by the failure of NADPH oxidase in phagocytic leukocytes to generate superoxide, needed for the killing of micro-organisms. The patients need careful management aimed at prevention and aggressive treatment of infections. CGD is a heterogeneous syndrome, both clinically and genetically. This disease is caused by a diversity of...

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Identifiers

PMID: 8070813
DOI: 10.1111/j.1600-065x.1994.tb00850.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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