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Article

Associations between variation in CHRNA5-CHRNA3-CHRNB4, body mass index and blood pressure in the Northern Finland Birth Cohort 1966.

PloS one - 1 Jan 2012

Kaakinen Marika, Ducci Francesca, Sillanpää Mikko J, Läärä Esa, Järvelin Marjo-Riitta

Abstract excerpt

BACKGROUND: The CHRNA5-CHRNA3-CHRNB4 gene cluster on 15q25 has consistently been associated with smoking quantity, nicotine dependence and lung cancer. Recent research also points towards its involvement in cardiovascular homeostasis, but studies in large human samples are lacking, especially on the role of the gene cluster in blood pressure regulation. METHODOLOGY/PRINCIPAL FINDINGS: We studied the associations...

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Source

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Identifiers

PMID: 23029550
DOI: 10.1371/journal.pone.0046557
PMCID: PMC3459914

Genes

CHRNA3
CHRNA5
CHRNB4
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Associations between variation in CHRNA5-CHRNA3-CHRNB4, body mass index and blood pressure in the Northern Finland Birth Cohort 1966.PMID 23029550Read ↗

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