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Article

Role of Abca7 in Mouse Behaviours Relevant to Neurodegenerative Diseases

24 Sept 2012

Abstract excerpt

ATP-binding cassette transporters of the subfamily A (ABCA) are responsible for the translocation of lipids including cholesterol, which is crucial for neurological function. Recent studies suggest that the ABC transporter ABCA7 may play a role in the development of brain disorders such as schizophrenia and Alzheimer's disease. However, Abca7's role in cognition and other behaviours has not been investigated....

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PMID: 23029339
DOI: 10.1371/journal.pone.0045959

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