Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA Sequences

24 Sept 2012

Abstract excerpt

Thiopeptides are a growing class of sulfur-rich, highly modified heterocyclic peptides that are mainly active against Gram-positive bacteria including various drug-resistant pathogens. Recent studies also reveal that many thiopeptides inhibit the proliferation of human cancer cells, further expanding their application potentials for clinical use. Thiopeptide biosynthesis shares a common paradigm, featuring a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to Microbial Natural Products and Biosynthesis
Share to Probiotics and Fermented Foods

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23029291
DOI: 10.1371/journal.pone.0045878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA SequencesPMID 23029291Read ↗

Bio-inspired engineering of thiopeptide antibiotics advances the expansion of molecular diversity and utility.Semantic proximity Read ↗

Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor TuSemantic proximity Read ↗

Bioactive Synthetic-Bioinformatic Natural Product Cyclic Peptides Inspired by Nonribosomal Peptide Synthetase Gene Clusters from the Human MicrobiomeSemantic proximity Read ↗

Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic BacteriaSemantic proximity Read ↗

Discovery and biosynthesis of persiathiacins: Unusual polyglycosylated thiopeptides active against multi-drug resistant tuberculosisSemantic proximity Read ↗

Thiopeptide Defense by an Ant’s Bacterial SymbiontSemantic proximity Read ↗

Automated genome mining predicts combinatorial diversity and taxonomic distribution of peptide metallophore structuresSemantic proximity Read ↗

Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutoniusSemantic proximity Read ↗

Biosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in <i>Actinobacteria</i>Semantic proximity Read ↗

Dithiolopyrrolone Natural Products: Isolation, Synthesis and BiosynthesisSemantic proximity Read ↗

Integrating genomics and metabolomics for scalable non-ribosomal peptide discoverySemantic proximity Read ↗

The Isolation of Pyrroloformamide Congeners and Characterization of Its Biosynthetic Gene Cluster from Streptomyces sp. CB02980 Revealed a Unified Mechanism for Dithiolopyrrolone BiosynthesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.