A 380-gene meta-signature of active tuberculosis compared with healthy controls

Abstract excerpt

Mycobacterium tuberculosis is estimated to have infected one third of the world's population and continues to be a significant cause of mortality and morbidity [1]. There is a need for new and improved diagnostics or treatment-monitoring tools and blood-based mRNA diagnostics are a potential solution [2]. Gene expression microarray analysis of human blood has been widely used to profile the host transcriptional...

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