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Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

26 Nov 2017

Abstract excerpt

Tuberculosis (TB) remains a major global health threat. Urgent needs in the fight against TB include improved and innovative treatment options for drug-sensitive and -resistant TB as well as reliable biological indicators that discriminate active from latent disease and enable monitoring of treatment success or failure. Prominent interferon (IFN) inducible gene signatures in TB patients and animal models of M....

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PMID: 29230217
DOI: 10.3389/fimmu.2017.01633

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