Article
Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis.
PloS one - 1 Jan 2011
Maertzdorf Jeroen, Ota Martin, Repsilber Dirk, Mollenkopf Hans J, Weiner January, Hill Philip C, Kaufmann Stefan H E
Abstract excerpt
Tuberculosis remains a major health threat and its control depends on improved measures of prevention, diagnosis and treatment. Biosignatures can play a significant role in the development of novel intervention measures against TB and blood transcriptional profiling is increasingly exploited for their rational design. Such profiles also reveal fundamental biological mechanisms associated with the pathology of the...
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