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Article

Interleukin 27 Induces the Expression of Complement Factor H (CFH) in the Retina

20 Sept 2012

Abstract excerpt

Complement factor H (CFH) is a central regulator of the complement system and has been implicated in the etiology of age-related macular degeneration (AMD), a leading cause of blindness in the elderly. In view of previous studies showing that reduced expression of CFH in the retina is a risk factor for developing AMD, there is significant interest in understanding how CFH expression is regulated in the retina. In...

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PMID: 23029250
DOI: 10.1371/journal.pone.0045801

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