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Article

Transcriptional regulation of the interleukin-11 gene by oncogenic Ras.

Carcinogenesis - 1 Dec 2012

Shin Soon Young, Choi Chan, Lee Hong Ghi, Lim Yoongho, Lee Young Han

Abstract excerpt

Interleukin-11 (IL-11), which belongs to a class of IL6-type cytokines, plays an important role in inflammation, motility and invasion in cancer. The ras mutation is frequently found in human cancer, but little is known regarding the transcriptional activation of the IL-11 gene by the Ras signal pathway in tumour cells. In this study, we investigated the role of Ras in the regulation of IL-11 using two different...

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Source

Identifiers

PMID: 23027619
DOI: 10.1093/carcin/bgs297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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