Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter.

The Journal of biological chemistry - 14 Mar 2003

Huang Xiu-li, Pawliczak Rafal, Yao Xiang-lan, Cowan Mark J, Gladwin Mark T, Walter M J, Holtzman M J, Madara Patricia, Logun Carolea, Shelhamer James H

Abstract excerpt

The effect of interferon (IFN)-gamma on p11 expression was studied in two human epithelial cell lines (BEAS-2B and HeLa). Treatment with IFN-gamma resulted in increased steady-state levels of p11 mRNA and protein expression, with a time-dependent and dose-dependent effect. Transient transfection experiments of a reporter gene construct containing 1498 bp of the 5'-flanking region of the p11 promoter demonstrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Annexin A2
Share to Calcium-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-gamma

Share to Oligonucleotides, Antisense

Share to Ribonucleases

Share to S100 Proteins

Share to STAT1 Transcription Factor

Share to Tyrosine

Source

Identifiers

PMID: 12645529
DOI: 10.1074/jbc.m212704200

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter.PMID 12645529Read ↗

p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation.Semantic proximity Read ↗

IFN-ε Mediates TNF-α-Induced STAT1 Phosphorylation and Induction of Retinoic Acid-Inducible Gene-I in Human Cervical Cancer CellsSemantic proximity Read ↗

Interferon-γ Inhibits STAT6 Signal Transduction and Gene Expression in Human Airway Epithelial CellsSemantic proximity Read ↗

Transcriptional regulation of the interleukin-11 gene by oncogenic Ras.Semantic proximity Read ↗

p48/STAT-1α-Containing Complexes Play a Predominant Role in Induction of IFN-γ-Inducible Protein, 10 kDa (IP-10) by IFN-γ Alone or in Synergy with TNF-αSemantic proximity Read ↗

STAT-phosphorylation-independent induction of interferon regulatory factor-9 by interferon-beta.Semantic proximity Read ↗

Transcriptional regulation of Tlr11 gene expression in epithelial cells.Semantic proximity Read ↗

Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gamma-inducible expression of human indoleamine 2,3-dioxygenase gene.Semantic proximity Read ↗

Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway.Semantic proximity Read ↗

IFN- gamma -dependent IL-7 gene regulation in keratinocytes.Semantic proximity Read ↗

Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells.Semantic proximity Read ↗

Microarray Analysis Identifies Interferon-Inducible Genes and Stat-1 as Major Transcriptional Targets of Human Papillomavirus Type 31Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.