Article
Cyclin D1 G870A polymorphism is associated with an increased risk of multiple myeloma.
Genetics and molecular research : GMR - 1 Jun 2015
Wang S, Huang Y, Su R, Fang Z, Han M
Abstract excerpt
Cyclin D1 is an important cell cycle regulator implicated in the pathogenesis of many cancer types. In particular, translocation and overexpression of cyclin D1 are common events in multiple myeloma (MM), suggesting that it may drive the initiation and progression of this malignancy. However, the association between genetic polymorphisms of cyclin D1 and the risk for developing MM remains poorly characterized. We...
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