Article
Generation and characterization of human cryptorchid-specific induced pluripotent stem cells from urine.
Stem cells and development - 1 Mar 2013
Zhou Junmei, Wang Xue, Zhang Shengli, Gu Yijun, Yu Ling, Wu Jing, Gao Tongbin, Chen Fang
Abstract excerpt
Cryptorchidism is a common congenital birth defect in human beings with the possible complication of infertility. An in vitro model of cryptorchidism might be valuable due to the inaccessibility of human embryos for research purposes. In this study, we reprogrammed urine cells containing genetic variations in insulin-like factor 3, zinc finger (ZNF) 214, and ZNF215 from a cryptorchid patient by introducing human...
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