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Article

miR-34c disrupts spermatogonial stem cell homeostasis in cryptorchid testes by targeting Nanos2

15 Oct 2018

Abstract excerpt

BACKGROUND: Cryptorchidism as a common genitourinary malformation with the serious complication of male infertility draws widespread attention. With several reported miRNAs playing critical roles in spermatogonial stem cells (SSCs), we aimed to explore the fundamental function of the highly conserved miR-34c in cryptorchidism. METHODS: To explore whether miR-34c participates in spermatogenesis by regulating...

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PMID: 30322389
DOI: 10.1186/s12958-018-0417-z

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